Best of all, shares of the company are historically cheap and producing a jaw-dropping annual yield. Investors can pick up Pfizer stock right now for an estimated 7 times forecast earnings for 2026. To boot, its nearly 8% dividend yield is nearing the highest level in the company's storied history.

Pointing to data showing run-ups in foreign purchases of U.S. stocks before the 1987 crash, the dot-com bubble in 2000, and the 2008 financial crisis, Ed Yardeni wrote in his eponymous research newsletter, "Their buying has a record of being a contrary indicator. They tend to be big buyers right before bear markets."

U.S. stocks fell Wednesday after Nvidia warned new restrictions on exports to China will chisel billions of dollars off its results, while companies around the world said President Donald Trump’s trade war is clouding forecasts for how they and the economy will do this year.