At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...

In eukaryotes, the cell cycle consists of four discrete phases: G 1, S, G 2, and M. The S or synthesis phase is when DNA ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a ...

New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...

"If it ain't broke, don't fix it," goes the old adage, which Rice University professor James Chappell completely ignored in a recent Nature Communications publication. In the study, Chappell describes ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV ...

A study headed by researchers at NYU Langone Health has found that herpes simplex virus 1 (HSV-1) partially liquifies the tightly packed, gel-like interior of human cell nuclei to help copy itself ...

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

New research shows that astroviruses, a leading cause of childhood diarrhea, co-opt the mucus-secreting machinery of ...