Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent. This means that millions of times a day a biochemical wonder takes place ...

DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH When cells in the human body divide, they must first make accurate copies of their DNA. The DNA ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

Scientists have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...