Researchers have found a new enzyme, taken from Flavobacterium akiainvivens, that has a much broader specificity than the current leading alternatives. This analysis resulted in the identification of ...

Transglutaminase 3 (TG3) belongs to a family of calcium-dependent enzymes which in sequence-specific fashions target Gln residues in polypeptides for posttranslational modifications 1. The reaction ...

The inversion of substrate size specificity is an evolutionary roadblock for proteins. The Duf4243 dioxygenases GedK and BTG13 are known to catalyze the aromatic cleavage of bulky tricyclic ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

This video explains how mechanical and chemical digestion break food down and how the small intestine’s adaptations increase ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Research published in The FEBS Journal may help overcome challenges to the treatment of malaria-a tropical disease caused by infection of red blood cells with Plasmodium parasites, which are ...

AMSBIO (Oxford, UK) has launched a new range of deubiquitinating (DUB) enzyme assay kits supplied in a convenient and easy-to-use 96-well assay format. With minimal setup required and no need for ...

Structure of a twisting BINOL radical shown with a P450 enzyme in the background. A BINOL radical twists within a P450 enzyme. Credit: S. Luke Schulert Students of stereochemistry know that chirality ...

Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...