A form of gene therapy administered to mice has been shown to protect optic nerve cells and help prevent vision loss or blindness from optic nerve damage and other serious retinal injury, and from ...

This is a preview. Log in through your library . Abstract Here, we use a mouse model (DBA/2J) to readdress the location of insult(s) to retinal ganglion cells (RGCs) in glaucoma. We localize an early ...

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH's National Eye Institute. The findings suggest a way forward ...

Although mammalian retinal ganglion cells (RGCs) normally cannot regenerate axons nor survive after optic nerve injury, this failure is partially reversed by inducing sterile inflammation in the eye.

PITTSBURGH--(BUSINESS WIRE)--Noveome Biotherapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing next-generation biologics for the promotion and restoration of cellular ...

In experiments in mouse tissues and human cells, researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged ...

Top row: Cross-sections through the mouse retina show very little free zinc (Zn2+) in normal mice (purple staining, left panel), but high levels after the optic nerve is injured (right panel). Within ...

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. When a car crash or explosion results in ...

Glaucoma is a serious eye disease that can gradually cause vision loss, which is currently irreversible. But in a new cell culture study scientists found that removing a membrane at the back of the ...

Connecting pieces of information by finding a common thread often takes glaucoma researchers in unexpected directions. Zinc is one such thread that joined together different experts at Boston Children ...