The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has uncovered a previously unknown regulatory mechanism in human cells.

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema of the internal ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

Parkinson’s disease is strongly linked to overactivation of a protein called LRRK2, but what turns this kinase on inside cells has remained unclear. In this study, we show that physical stress on ...

Lysosomes are small compartments inside cells that break down and recycle biological materials. Once regarded mainly as cellular waste-disposal centers, lysosomes are now understood to be important ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...