Nature

Transformation of severe congenital neutropenia to early acute lymphoblastic leukemia in a patient with HAX1 mutation and without G-CSF administration or receptor mutation

The diagnosis of severe congenital neutropenia (SCN) is clinically based on profound persistent neutropenia (absolute neutrophil count (ANC). We previously reported on an SCN patient who transformed ...
JSTOR Daily

Tissue-Specific Transformation by Epidermal Growth Factor Receptor: A Single Point Mutation within the ATP-Binding Pocket of the erbB Product Increases its Intrinsic Kinase ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 23 (Dec., 1990), pp. 9103-9107 (5 pages) Avian c-erbB is activated to a leukemia oncogene following ...