Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States' fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

Researchers used emergent MRI technology to understand the impact of prenatal opioid exposure on early brain development and the neural mechanism behind current medications. “Choose life. Choose a job ...

Synthetic opioids like fentanyl are now the main drivers of fatal overdoses in the US, yet current treatment of the addiction is haphazard and often prohibitive. But new research has uncovered a ...

July 11 (UPI) --While scientists have long noted a complex connection between a person's addiction to opiates, or "opioid use disorder," and chronic pain, the brain mechanisms linking the two have ...

Endogenous opioid peptides are the neurochemical basis of the anesthetic and analgesic effects of acupuncture. The quantity of acupuncture stimulus can be controlled accurately by using ...

Porchbox made by Mechanism Exchange & Repair in Yoakum. Mechanism Exchange & Repair, one of the last manufacturers of newspaper vending machines, is finding their distribution boxes make their way ...

Scientists have discovered that the body can naturally dull pain through its own localized “benzodiazepine-like” peptides. A groundbreaking study led by a University of Leeds scientist has unveiled ...

Listening to a favorite song can trigger a profound emotional response that rivals the feelings produced by biological ...