Researchers have identified a dual therapeutic strategy that combined inhibition of a key SARS-CoV-2 viral enzyme with suppression of a host inflammatory pathway, with preclinical evidence that ...

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Microscope image of human epithelium cells (blue) infected with SARS-CoV-2 (red), showing the virus spreading from one cell to another. LA JOLLA, CA—Despite vaccines and treatments, SARS-CoV-2—the ...

Researchers from the Institute for Basic Science of Korea and collaborating institutions have designed a new class of peptide-based inhibitors targeting a crucial interface within the SARS-CoV-2 ...

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

Forget about locating molecules in the blink of an eye, which takes as long as a quarter second—far too long a time to distinguish a sequence of subcellular events. Instead, try doing what Stanford ...

Young infants hospitalized with respiratory syncytial virus (RSV) often become much sicker than those infected with ...

Since the start of the COVID-19 pandemic, there has been controversy surrounding the origins of SARS-CoV-2. New research from the University of California, San Diego (UCSD), School of Medicine ...

Two of the closest known relatives to SARS-CoV-2 — a pair of bat coronaviruses discovered by researchers in Laos — may transmit poorly in people despite being genetically similar to the ...