We found four breast cancer risk prediction models that had been tested enough times to evaluate in detail. These were the Gail, Tyrer-Cuzick, BOADICEA, and BRCAPRO models. The BOADICEA model was one ...

Botox-A may provide a slight short-term improvement in pain (6%) which does not extend to the long term. People may report treatment success (20%) in both the short and long term. There may be no ...

Compared with trapeziectomy (removal of the bone at the base of the thumb), trapeziectomy with LRTI (replacing the ligament and strengthening the joint with tendon from the forearm) may provide little ...

COPD is a common and long-term lung condition that slowly worsens over the years, and causes symptoms such as breathlessness, coughing, wheezing and increased sputum (mucus) production. This leads to ...

To determine the effects of the Pilates method for patients with non-specific acute, subacute or chronic low back pain. This review included 10 studies and 510 patients. All studies included a similar ...

The available evidence suggests that a course of acupuncture consisting of at least six treatment sessions can be a valuable option for people with frequent tension-type headache. Tension-type ...

What is the aim of this review? We aimed to find out whether brief interventions with doctors and nurses in general practices or emergency care can reduce heavy drinking. We assessed the findings from ...

Do omega-3 long chain polyunsaturated fatty acids (LCPUFA) taken during pregnancy - either as supplements or as dietary additions in food (such as some types of fish) - improve health outcomes for ...

Drugs that target amyloid beta proteins in the brain likely have no clinically meaningful positive effects, while increasing the risk of bleeding and swelling in the brain, a new Cochrane review has ...

Newly updated evidence published in the Cochrane Library today compares Alcoholics Anonymous (AA) and clinically-related Twelve-Step Facilitation (TSF) programs with other treatments, such as ...

Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they ...

Falls by older people in care facilities, such as nursing homes, and hospitals are common events that may cause loss of independence, injuries, and sometimes death as a result of injury. Effective ...