San Francisco 49ers defensive back Deommodore Lenoir takes fans inside his biggest career moments in this episode of "Inside the Play" presented by Microsoft Surface Pro.

If you hopped in your motor vehicle in Cleveland, and drove cross-country, your journey to San Francisco, would cover 2,456 ...

ESPN's Jeremy Fowler reports DJ Reed has become the most sought-after cornerback in the 2025 NFL Free Agency market.

While the 49ers need help in the trenches, NBC Sports Bay Area’s Matt Maiocco has San Francisco going in a completely different direction in his latest Mock Draft.

Who has the best NFL defense in 2025? Our weekly NFL defense rankings examine every unit across the league every ...