SANTA FE, N.M. (AP) — Actor Gene Hackman died of heart disease a full week after his wife died from hantavirus in their New Mexico home, likely unaware that she was dead because he was in the advanced stages of Alzheimer’s disease, authorities revealed Friday.

As cops scramble to piece together what caused the tragic deaths of Gene Hackman and his wife, friends of the couple lament how they had become increasingly insular in their final years and even stopped receiving guests.