San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

The 49ers saw top draft pick Mykel Williams exit with a hyperextended knee in their spirited joint practice with the Denver ...

Christian McCaffrey credited his wife, Olivia Culpo, for taking care of their newborn daughter while he's at San Francisco ...

Christian McCaffrey shared he feels dad guilt leaving Olivia Culpo home with baby Colette as he trains for the NFL season ...

Since quarterback Brock Purdy took over as the 49ers' starting quarterback midway through the 2022 season, the team's offense ...

Evaluating the risk-factors of Christian McCaffrey and his ability to be drafted in the first round of your fantasy football ...

San Francisco 49ers running back Christian McCaffrey joins NFL Network's David Carr and NFL Network Insider Mike Garafolo on ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

When the 49ers offense is healthy, it's one of the best in the NFL. Unfortunately, their offense wasn't healthy last year, and it isn't healthy now.

As the 49ers’ starting quarterback, Brock Purdy has revealed the play he considers his favorite. Purdy has produced 70 touchdowns in red and gold since taking o ...

All signs point to Aiyuk starting the season on the reserve/PUP list, which would sideline him for the first four weeks of ...