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  1. NMDA receptor - Wikipedia

    The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca 2+ ion channel found in neurons. [3][4] The NMDA …

  2. Physiology, NMDA Receptor - StatPearls - NCBI Bookshelf

    Dec 11, 2022 · The N-methyl-D-aspartate (NMDA) receptor is a glutamate receptor, the human brain's primary excitatory neurotransmitter. It plays an integral role in synaptic plasticity, a …

  3. What are NMDA Receptors? - News-Medical.net

    Nov 24, 2024 · N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by an excitatory neurotransmitter, glutamate.

  4. NMDA receptor functions in health and disease: Old actor, new ...

    Dupuis et al. discuss recent advances in our understanding of the glutamatergic NMDA receptor, focusing mainly on the dynamics and nanoscale organization of membrane NMDA receptors …

  5. The NMDA Receptor: Function, Disease, and Medications

    Jul 20, 2025 · N-methyl-D-aspartate (NMDA) is an amino acid derivative, known for the protein it selectively binds to in the brain: the NMDA receptor. This receptor is a protein on the surface …

  6. NMDA Receptor - an overview | ScienceDirect Topics

    NMDA receptors (NMDARs) are defined as prominent ligand-gated ion channels that play a crucial role in excitatory synaptic transmission in the central nervous system, and are essential …

  7. NMDA receptors in the central nervous system - PMC

    Here, we will review the relationship between NMDA receptor structure and function, the diversity and significance of NMDA receptor subtypes in the CNS, as well as principles and rules by …

  8. What Is the NMDA Receptor and Why Is It Important?

    Jul 19, 2025 · The NMDA receptor is a type of ion channel, a pore in the cell membrane that can open or close to allow charged particles, called ions, to pass through. When it opens, it …

  9. NMDA Receptors in Neurodevelopmental Disorders: …

    NMDA receptors (NMDARs) are cation-specific ligand-gated ion channels that mediate glutamatergic synaptic transmission throughout the CNS. The NMDARs are localized on …

  10. Activation Mechanisms of the NMDA Receptor - Biology of the NMDA

    NMDA receptors (NMDARs) are glutamate-gated cation channels with high calcium permeability that play important roles in many aspects of the biology of higher organisms.